Rapid pharmacotherapeutic intervention for an influenza A outbreak in the Canadian Arctic: lessons from the Sanikiluaq experience.
Identifieur interne : 000987 ( Main/Exploration ); précédent : 000986; suivant : 000988Rapid pharmacotherapeutic intervention for an influenza A outbreak in the Canadian Arctic: lessons from the Sanikiluaq experience.
Auteurs : P. Van Caeseele [Canada] ; A. Macaulay ; P. Orr ; F. Aoki ; B. MartinSource :
- International journal of circumpolar health [ 1239-9736 ] ; 2001.
Descripteurs français
- KwdFr :
- Acides sialiques (usage thérapeutique), Adulte, Adulte d'âge moyen, Antiviraux (usage thérapeutique), Canada (épidémiologie), Femelle, Flambées de maladies, Grippe humaine (diagnostic), Grippe humaine (traitement médicamenteux), Grippe humaine (virologie), Grippe humaine (épidémiologie), Grossesse, Guanidines, Humains, Pyrannes, Régions arctiques (épidémiologie), Sujet âgé, Trousses de réactifs pour diagnostic, Virus de la grippe A (isolement et purification), Zanamivir.
- MESH :
- diagnostic : Grippe humaine.
- isolement et purification : Virus de la grippe A.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Acides sialiques, Antiviraux.
- virologie : Grippe humaine.
- épidémiologie : Canada, Grippe humaine, Régions arctiques.
- Adulte, Adulte d'âge moyen, Femelle, Flambées de maladies, Grossesse, Guanidines, Humains, Pyrannes, Sujet âgé, Trousses de réactifs pour diagnostic, Zanamivir.
- Wicri :
- geographic : Canada.
English descriptors
- KwdEn :
- Adult, Aged, Antiviral Agents (therapeutic use), Arctic Regions (epidemiology), Canada (epidemiology), Disease Outbreaks, Female, Guanidines, Humans, Influenza A virus (isolation & purification), Influenza, Human (diagnosis), Influenza, Human (drug therapy), Influenza, Human (epidemiology), Influenza, Human (virology), Middle Aged, Pregnancy, Pyrans, Reagent Kits, Diagnostic, Sialic Acids (therapeutic use), Zanamivir.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Sialic Acids.
- geographic , epidemiology : Arctic Regions, Canada.
- diagnosis : Influenza, Human.
- drug therapy : Influenza, Human.
- epidemiology : Influenza, Human.
- isolation & purification : Influenza A virus.
- virology : Influenza, Human.
- Adult, Aged, Disease Outbreaks, Female, Guanidines, Humans, Middle Aged, Pregnancy, Pyrans, Reagent Kits, Diagnostic, Zanamivir.
Abstract
In January of 2000 an outbreak of influenza-like illness (ILI) was identified by Health Centre nursing staff in the remote island Inuit community of Sanikiluaq, Nunavut. A staged approach to an intervention strategy was adopted and an intervention team dispatched within 48 hours with diagnostic, prophylactic, and therapeutic capabilities and the intent to evaluate the response as well. The presence of influenza virus was determined on site in 3 out of thirteen initial cases of ILI using portable kit based rapid detection. This permitted the use of zanamivir (an inhaled neuraminidase inhibitor) for prophylaxis in 201, and for treatment in 12 persons. Amantadine was only used in 16 and 52 were ineligible for medical intervention, mostly because they fell outside of the window of opportunity or for maternal/reproductive reasons. The intervention strategy framework adopted was felt to be successful and is presented for consideration in future intervention initiatives.
PubMed: 11768446
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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A staged approach to an intervention strategy was adopted and an intervention team dispatched within 48 hours with diagnostic, prophylactic, and therapeutic capabilities and the intent to evaluate the response as well. The presence of influenza virus was determined on site in 3 out of thirteen initial cases of ILI using portable kit based rapid detection. This permitted the use of zanamivir (an inhaled neuraminidase inhibitor) for prophylaxis in 201, and for treatment in 12 persons. Amantadine was only used in 16 and 52 were ineligible for medical intervention, mostly because they fell outside of the window of opportunity or for maternal/reproductive reasons. 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PubStatus="entrez"><Year>2002</Year><Month>1</Month><Day>5</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11768446</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country><region><li>Manitoba</li></region><settlement><li>Winnipeg</li></settlement><orgName><li>Université du Manitoba</li></orgName></list><tree><noCountry><name sortKey="Aoki, F" sort="Aoki, F" uniqKey="Aoki F" first="F" last="Aoki">F. Aoki</name><name sortKey="Macaulay, A" sort="Macaulay, A" uniqKey="Macaulay A" first="A" last="Macaulay">A. Macaulay</name><name sortKey="Martin, B" sort="Martin, B" uniqKey="Martin B" first="B" last="Martin">B. Martin</name><name sortKey="Orr, P" sort="Orr, P" uniqKey="Orr P" first="P" last="Orr">P. Orr</name></noCountry><country name="Canada"><region name="Manitoba"><name sortKey="Van Caeseele, P" sort="Van Caeseele, P" uniqKey="Van Caeseele P" first="P" last="Van Caeseele">P. Van Caeseele</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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